Vendetta is a cooperative deductive murder mystery game where players must solve puzzles, follow clues and make decisions to solve a case. They do this using the included deck of cards, 12 hidden realistic clue documents, and the Internet. Through a choose-your-own-adventure mechanism, players make decisions that influence the course of the game and lead to solving the case in the end. One by one, they enter different realistically designed locations and encounter the various suspects. Then they choose from 3 different ways to deal with the situation and receive points based on their decisions. Complex puzzles and escape room elements must be solved in order to progress further in the case.

Thematically, the game moves in the environment of the mafia in today's New York. As a member of the mafia you have to uncover the mole in your own ranks who caused the death of the eldest son of the godfather. It's up to you whether you act morally or use other methods to make your victims talk. The game is closely intertwined with the real world, and players have to keep using traditional apps like Google Maps or Wikipedia to gather information. Writing emails, detailed web pages and cell phone calls are also part of the immersive gaming experience.