Supergirl...the Infected! In protecting Superman, Supergirl becomes infected by a virus created by the Batman Who Laughs, turning her into the twisted Dark Multiverse version of herself. Batman and Superman enlist the help of Wonder Woman to bring Kara back peacefully, but is it too late to save her? And if Supergirl is able to return to her old self, can she hope to redeem herself after putting Smallville in danger?

Collects Supergirl #34-42, Supergirl Annual #2, and a story from Superman: Leviathan Rising Special #1.