We all remember when the Scarlet Witch uttered the three words that would change the landscape of the Marvel Universe: 'No More Mutants!' But what if she said something different? And what of the consequences…? In a world without great power, who bears the burden of responsibility? Who will stand up to an enemy who fills the vacuum of power and whose hatred is unparalleled? Brian Reed (SECRET INVASION: FRONT LINE) with Marvel's own Jim McCann and brand-spankin' new artist Paolo Pantalena answer the question: 'What if Scarlet Witch had ended the HOUSE OF M by saying 'NO MORE POWERS!' Also featuring Part 1 of a special five part back-up story in all the What Ifs this year, in which we see Iron Lad take a different path that leads him to recruit a different set of future Avengers. Join C.B. Cebulski (X-MEN: DIVIDED WE STAND, LONERS) and Patrick Spaziante (MUTIES, Sonic The Hedgehog) as they ask, 'What if the Runaways Became the Young Avengers?'