The intergalactic Mission Appleseed to perpetuate humankind by seeding the stars continues, leaping ahead twenty two years. Children no more, Alex, Gem and Goldie prepare to embark on the colonizing quest for which they've prepared their entire lives. With Raj complicit, Gem's dark secret is revealed and the idyllic repetition of the next phase of the Mission is shattered by sabotage, implicating the sinister embedded terrorist group known only as Awake. Treachery forever alters the latest iteration of the Mission, tearing lifelong lovers apart and plunging their Mission into uncertainty.