As Etrigan and Jason Blood adapt to their new forms in the hell zone engulfing Death Valley, they find themselves in the presence of a seemingly psychic child, otherwise unaffected by the nuclear hell blast. But before they can address the mystery of this child, they must fight their way to an old companion, Madame Xanadu, who is trapped in a roadside hotel of hell. As hell continues to spew into Earth, Blood must try and contain an unhinged Etrigan, capable of harming everyone around them, including his companions.